L. Yu
2015
Citations
0
Influential Citations
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Citations
Journal
Polymer Bulletin
Abstract
Morpholine-2,5-dione derivatives are a kind of cyclic monomers for the preparation of biodegradable materials.This paper summarized the synthesis methods of morpholine-2,5-dione derivatives and their copolymers,as well as their potential applications in medical field.Firstly,three synthesis methods of these derivatives were introduced,also the homopolymerization of morpholine-2,5-dione derivatives to prepare polydepsipeptides was summarized.Secondly,this paper introduced ring-opening copolymerization of morpholine-2,5-dione derivatives with e-caprolactone and lactide to prepare the copolymers based on amino acids.Finally,this paper summarized the synthesis of morpholine-2,5-dione derivatives block copolymers,and the recent development of their applications in drug delivery and gene carriers.