Z. Hen
2014
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Journal
Chemical Propellants & Polymeric Materials
Abstract
The physico-chemical properties,spectral properties and applications of an important fluorinecontaining fine chemical product and pharmaceutical intermediate—4,4'-difluorobenzophenone are introduced.The synthesis and research situations of 4,4'-difluorobenzophenone at home and abroad are reviewed.Its synthesis methods mainly include the Fridel-Crafts alkylation hydrolysis method,Fridel-Crafts acylation method,halogen substitution method,diazotization oxidation method,catalytic carbonylation method,4,4'-difluorodiphenyldichloroethylene oxidation method,4,4'-difluorodiphenylmethane oxidation method and so on.