C. Cantisani, Serafino Ricci, T. Grieco
Nov 19, 2013
Citations
0
Influential Citations
38
Citations
Quality indicators
Journal
BioMed Research International
Abstract
Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function.