Y. Fukase, K. Fukase, S. Kusumoto
Feb 5, 1999
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The propargyloxycarbonyl group readily introduced to both amino and hydroxy groups by using propargyl chloroformate is stable to neat TFA but is readily cleaved at ambient temperature by treatment with Co 2 (CO) 8 and TFA in CH 2 Cl 2 via formation of an alkyne-Co complex. The propargyl ester similarly serves as a good protecting group for carboxy functions.