K. Kawashima, H. Itoh, Kazuo Matsumoto
Jul 25, 1979
Citations
0
Influential Citations
2
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
N-Methyl-3-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid (MDTI), a new chemical compound, was prepared by cyclization of α-methyl-α-(3, 4-methylenedioxybenzyl)-α-aminoacetonitrile with formaldehyde and formic acid, followed by hydrolysis with hydrochloric acid. The compound (MDTI) showed extremely high electron-donating activity and was found to have excellent antioxidant properties.