W. Wieslaw, S. Krystyna, Czaplewski Cezary
Jan 22, 1997
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0
Influential Citations
12
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Journal
Journal of Photochemistry and Photobiology A-chemistry
Abstract
Abstract Photophysical properties of ( p -hydroxy)phenylglycine [Phg(OH)] (an analogue of tyrosine) and its derivatives with the unmodified hydroxyl group; AcPhg(OH)OH, Phg(OH)NHCH 3 , AcPhg(OH)NHCH 3 , and the derivatives with the methylated phenolic hydroxyl group: Phg(OCH 3 ), AcPhg(OCH 3 )OH, Phg(OCH 3 )NHCH 3 , AcPhg(OCH 3 )NHCH 3 were the subject of our investigations. The synthesized compounds were used to study the influence of (i) the conversion of the carboxylic group into the amide, (ii) the N -acetylation of the amino group and (iii) the O -methylation of the phenolic oxygen on the photophysical properties of the tyrosine analogue. All prepared derivatives displayed monoexponential fluorescence decays. The N -acetylation and amidation decreased the fluorescence lifetime of the resulting compounds. The data obtained are discussed on the basis of the rotamer theory and compared with theoretical calculations results.