M. Ikaunieks, M. Madre
Feb 1, 2003
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Influential Citations
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Journal
Chemistry of Heterocyclic Compounds
Abstract
S-Alkylation of 2-acetamido-9-(2-acetoxyethoxymethyl)-6-oxo-8-thioxopurine was used to synthesize its novel S- and N(7)-substituted derivatives. We have established the effect of the structure of the alkylating agent on the reaction conditions and its regioselectivity. We have shown that the synthesized guanine derivatives can be modified further.