P. Olesen, T. Kappe, J. Becher
Nov 1, 1988
Citations
0
Influential Citations
6
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The nucleophilic substitution of halogen in 3,5-dichloro-6-phenylpyridazine 1, 5-chloro-2-methyl-6-phenylpyridazin-3(2H)-one 13 as well as in 3-chloro-2-methyl-6-phenylpyridazin-5(2H)-one 14 with methoxy, ethoxy and the 2-methyl-2-propanethiolate anion is described. In the last type of compounds the t-butylthio groups can be eliminated regioselectively with Lewis acids, resulting in the formation of monomercapto and mono-thiopyridazines.