J. D. Hunt, A. Mckillop*
1964
Citations
1
Influential Citations
14
Citations
Journal
Journal name not available for this finding
Abstract
Publisher Summary This chapter highlights pyridine and piperidine alkaloids. The key bases of pyridine and piperidine, and some of their simple derivatives are available in nature. Piperidine is found in pepper, tobacco and several other plants. Pepper also contains the amorphous alkaloid chavicine, which is isomeric with piperine. Hydrolysis yields piperidine and chavicic acid, which is a geometrical isomer of piperic acid. Chavicine is therefore, the piperide of chavicic acid. Various alkaloids of pyridine and piperidine are discussed briefly in this chapter. Piperine is a very weak base, which is hydrolyzed by acid or alkali. Piperine is formed by the action of piperidine on piperyl chloride. Trigoaelline is available in a wide variety of plants, including coffee and potato. It affords methylamine when heated with alkali, and it gives nicotinic acid and methyl chloride when heated with hydrochloric acid. Rieinine is an alkaloid, which is found in the seeds of the castor oil plant. It is a neutral, optically inactive compound, which yields pyridine on zinc dust distillation. Three new alkaloids, such as lythranine, lythranidine and lythramine have been isolated from Lythrum anceps. These are assigned their basic skeletal forms based on the results of their chemical and spectroscopic studies.