O. Burova, N. Smirnova, T. S. Safonova
Mar 1, 1993
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Journal
Chemistry of Heterocyclic Compounds
Abstract
The reaction of 5,7-dichloro-6-nitropyrido[2,3-d]-pyrimidine-2,4-dione with amines gave products of the substitution of one or two chlorine atoms by ammo groups. The catalytic reduction of 6-nitro-5,7-disubstituted pyrido[2,3-d]pyrimidines with hydrogen over palladium oxide on carbon leads to 5,6-diamino- and 5,6,7-triaminopyridopyrimidines, the reaction of which with amyl nitrite in acetic acid gives triazolo(4′,5′:4,5) pyrido[2,3-d]pyrimidines.