K. Hirota, K. Banno, Y. Yamada
1985
Citations
0
Influential Citations
21
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
Reaction of 5-bromo-6-methyluracil derivatives (1), possessing a phenyl or para-substituted phenyl group at the 1-position of the uracil ring, with methylamine and hydrazine hydrate causes novel ring transformations to give 1-arylhydantoins (2) and 4-ureidopyrazol-3-ones (9), respectively. The latter conversion into the pyrazolone (9) is a double ring transformation via a hydantoin intermediate (IV).