C. M. Rubin, C. Schmid
Oct 24, 1980
Citations
3
Influential Citations
219
Citations
Quality indicators
Journal
Nucleic acids research
Abstract
Potassium permanganate reacts selectively with thymidine residues in DNA (1) while hydroxylamine hydrochloride at pH 6 specifically attacks cytosine (2). We have adopted these reactions for use with the chemical sequencing method developed by Maxam and Gilbert (3).