H. J. Anderson, C. Riche, T. Costello
Mar 1, 1978
Citations
0
Influential Citations
19
Citations
Journal
ChemInform
Abstract
2-Pyrrolecarbonitrile has been acylated to its 4-formyl, trichloroacetyl, ester, and thiolester derivatives. Further reactions gave other 2,4-difunctionalized compounds. These included conversion of the 2-nitriles to the corresponding 2-aldehydes. Subsequent removal of the aldehyde group afforded several 3-substituted pyrroles in good yield.