Fengyu Bao, Xiaobing Wang, L. Kong
Mar 13, 2013
Citations
0
Influential Citations
4
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A novel domino reaction catalyzed by an organic molecule based on α,β-unsaturated aromatic aldehydes and methylethylketones has been developed. The progress allows one-pot and efficient synthesis of polysubstituted 4-oxocyclohexanecarbaldehyde derivatives via pyrrolidine mediated under mild conditions. The reaction consists of three consecutive reactions: an aldol condensation reaction and a tandem inter-Michael–intra-Michael addition reaction.