V. Modesto-Lowe, Agata Harabasz, Sophia A. Walker
May 1, 2021
Citations
1
Influential Citations
19
Citations
Journal
Cleveland Clinic Journal of Medicine
Abstract
The second-generation antipsychotic drug quetiapine (Seroquel) is increasingly being used off-label for treating insomnia in the general population, possibly to avoid standard medications with known addictive qualities and adverse side effects. However, evidence to support using it in this way is scant, and quetiapine is associated with weight gain and other metabolic effects. It must be used cautiously and with appropriate monitoring for adverse effects and abuse. Its cardiometabolic effects and potential for abuse warrant caution in off-label use.