G. Atassi, H. Tagnon
Sep 1, 1975
Citations
0
Influential Citations
33
Citations
Journal
European journal of cancer
Abstract
Abstract R 17934 -NSC 238159 : methyl[ 5 -( 2 -thienyl carbonyl)- 1 H-benzimidazol- 2 yl] carbamate, a new antitumor agent was found active against lymphoid L 1210 leukemia, lymphocytic P 388 leukemia, melanotic melanoma B 16 and Lewis Lung carcinoma. This activity was influenced by the vehicle used in the preparation of the suspension and the route of administration of the drug, and to a lesser extent by the schedule of administration. The low toxicity of therapeutically active doses singles out this compound for possible clinical application.