T. Itahara, N. Ide
Aug 1, 1992
Citations
0
Influential Citations
9
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Reaction of 1,3-dimethyluracil and 1,3,6-trimethyluracil with benzoyl peroxide in cyclohexane, ethyl acetate, and acetonitrile gave the corresponding 5-alkyl-1,3-dimethyluracils, although a steric effect of the methyl group at 6-position complicated the reaction. On the other hand, a similar treatment of 1,3-dimethylthymine led to alkylation of the methyl group at 5-position. The reaction of caffeine gave 8-alkylcaffeines and alkyl acetates were used as favorable solvents with respect to synthesis of 8-alkylcaffeines.