R. Fujita, M. Hoshino, Tsuyoshi Taguchi
Dec 1, 2007
Citations
0
Influential Citations
12
Citations
Journal
Heterocycles
Abstract
Reactions between active methylene compounds and 2-alkyllthio-l-alkylpyridinium iodides in the presence of sodium hydride, were found to occur at the 2 or 4-position. In contrast, 2-chloro-l-methylpyridinium iodide reacted at the 2-position, whereas 6-chloro-2-methylthiopyridinium iodide reacted at the 6-position to yield only one product. Chemoselectivity of the pyridinium salt was calculated using molecular orbital (MO) calculations.