K. F. Suzdalev, S. V. Den’kina, G. Borodkin
Nov 11, 2011
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron
Abstract
Reaction of 2-chloroindole-3-carbaldehyde with epibromohydrin gives the expected 1-(oxiran-2ylmethyl) derivative. However the analogous reaction with epichlorohydrin leads to the formation of the oxazolo[3,2-a]indole skeleton. Some chemical properties of this tricyclic system were investigated. Its reaction with secondary amines unexpectedly proceeds with the opening of the oxazole ring.