S. V. Fedoseev, A. Ershova, K. V. Lipin
Aug 1, 2021
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Journal
Russian Journal of Organic Chemistry
Abstract
The reaction of 2-chloropyridine-3,4-dicarbonitrile with anilines in propan-2-ol in the presence of N,N- diisopropylethylamine (DIPEA) in a sealed vial at 120°С involves the nucleophilic substitution of chlorine and yields 2-(arylamino)pyridin-3,4-dicarbonitriles.