R. Aggarwal, Garima Sumran, R. Kumar
Oct 23, 2007
Citations
1
Influential Citations
11
Citations
Journal
Arkivoc
Abstract
Treatment of 2-hydrazino-3-methylquinoxaline (1) with phenyl-1,3-butanedione (2b) in THF affords regioisomeric 1-(3’-methylquinoxalin-2’-yl)-3(5)-methyl-5(3)-phenylpyrazoles (3b and 4b) as major products along with the formation of small amount of 1,4-dimethyl-1,2,4triazolo[4,3-a]quinoxaline (5) rather than the reported exclusive formation of 5. Several other regioisomeric 1-(3’-methylquinoxalin-2’-yl)-3,5-disubstituted pyrazoles have similarly been synthesized using other aryland heteroaryl-1,3-diketones. The identity of the regioisomeric pyrazoles is based upon NMR (H & C) spectral data and an unambiguous synthesis.