V. Montoya, J. Pons, J. García‐Antón
Sep 1, 2007
Citations
0
Influential Citations
26
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract The reaction of the β-diketone 4,4,4-trifluoro-1-pyridin-2-yl-butane-1,3-dione and the monosubstituted hydrazine 2-hydroxyethylhydrazine has been investigated. Two products have been identified, 2-(2-hydroxyethyl)-3-pyridin-2-yl-5-trifluoromethyl-4,5-dihydropyrazole ( P ) and 2-(3-pyridin-2-yl-5-trifluoromethylpyrazol-1-yl)ethanol ( L ) in proportion 2:8, when the reaction was done at room temperature in ethanol for 15 h. The preparation of P as a pure product was performed in ethanol at 0 °C for 7 h. P has been characterized by 1 H, 13 C{ 1 H} and 19 F{ 1 H} NMR spectroscopy and by other techniques as appropriate.