S. Azimi, J. Azizian
Jan 13, 2016
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron Letters
Abstract
An efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones proceeding via a three-component reaction between benzyl alcohols, isatoic anhydride, and primary amines in the presence of iodine and potassium carbonate is reported. This protocol allows the straightforward preparation of the titled products using readily available benzyl alcohols instead of unstable aldehydes under mild oxidative conditions.