M. Demuth, P. Raghavan
Oct 31, 1979
Citations
0
Influential Citations
20
Citations
Journal
Helvetica Chimica Acta
Abstract
Cyclopropyl ketones are readily cleaved under neutral conditions at room temperature by the combined action of acetyl methanesulfonate and nucleophiles such as Br−, I−, and MsO−. The high-yield reaction involves regiospecific enol acetate formation with a stereoselectivity of nucleophile addition which is compatible with an SN2-type opening of the cyclopropyl ring.