B. Cho, Namdu Kim
1996
Citations
0
Influential Citations
20
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
A series of new 1,2-O-isopropylidene-5-deoxy-5-N,N-dialkyl (or-N-monoalkyl)amino-α-D-xylofuranose derivatives have been prepared form D-xylose and their enantioselectivities as chiral catalysts for the addition of diethylzinc to aldehydes have been examined. Or the chiral catalysts examined, 5-deoxy-1,2-O-isopropylidene-5-morpholino-α-D-xylofuranose provides high enantioselectivity for aromatic and relatively hindered aliphatic aldehydes, and 5-deoxy-5-hexaydroazepinyl-1,2-O-isopropylidene-α-D-xylofuranose is highly effective for unhindered aliphatic aldehydes.