S. Pil'o, V. Brovarets, E. A. Romanenko
Nov 1, 2002
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0
Influential Citations
2
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Journal
Russian Journal of General Chemistry
Abstract
Polychlorinated enamidonitrile Cl2CÍC(CN)NHCOCHCl2 readily reacts with primary aromatic amines, dialkylamines, piperidine, and morpholine. The reaction is accompanied by complete elimination of chlorine atoms as chloride ions with formation of 4-cyanooxazoles having the corresponding amine residue in position 5 of the ring and a CHÍN or diaminomethyl moiety in position 2. The structure of 5-arylamino(dialkylamino)-4-cyano-2-formyloxazoles was confirmed by their acid hydrolysis, as well as by the condensation with phenylhydrazine, N-alkylrhodanines, and ethyl acetoacetate in the presence of urea.