David E Stephens, Yu Zhang, M. Cormier
Jun 25, 2013
Citations
0
Influential Citations
53
Citations
Journal
Chemical communications
Abstract
A novel stereospecific three-component reaction of aziridines and azetidines with arynes and acetonitrile has been developed. The reaction affords N-aryl γ-aminobutyronitriles and δ-aminovaleronitriles that can be used as precursors and congeners of a number of bioactive compounds, such as pregabalin and lergotrile.