V. Yakubkene, P. Vainilavichyus
Aug 1, 1998
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Influential Citations
2
Citations
Journal
Chemistry of Heterocyclic Compounds
Abstract
The reaction of 6-methyl-2-methylthio-3-(2-thioxo-1,3,4-oxadiazol-5-yl)methyl-4(3H)-pyrimidinone with butyland benzylamine and also with piperidine and morpholine has been studied. It was found that the primary amines not only open the 1,3,4-oxadiazole ring to form the corresponding thiosemicarbazides but also substitute the methylthio group at position 2 in the pyrimidine ring. Morpholine can only open the 1,3,4-oxadiazole ring but piperidine can also substitute the methythio group to give an oxadiazolethione piperidinium salt.