A. S. Youssef
2009
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0
Influential Citations
1
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Journal
Afinidad
Abstract
Reactions of 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b] thiophene (1a) with arylidenemalononitriles 2a-c gave the benzothieno[2,3-d]pyrimidine derivatives 3a-c as E,Zmixtures as well as Z-3c and E-3c isomers in case of 2c. Similar treatment of 6-amino-1,4-dihydro-1,4-diphenyl-5- cyano-3-methylpyrano[2,3-c]pyrazole (4) with 2b,d yielded the pyrazolopyranopyrimidine derivatives 5a,b as Z- and E- steroisomers. Treatment of 4 with acetylenic esters and ketones 6a-d afforded the ethenylaminopyrano[2,3-c]pyrazole derivatives Z-(7a-d). Reacting 1a with 6c-e gave the aroylmethylenebenzamidobenzo[b]thiophene derivatives 8ac. Structures of all products are evidenced by microanalytical and spectral data.