M. Sallam, M. H. Elnagdi, M. Abdel-Hady
Nov 5, 1975
Citations
0
Influential Citations
2
Citations
Journal
Helvetica Chimica Acta
Abstract
Benzo[b]thiophene-2,3-diones (1) react with Grignard reagents to yield 2,3-dihydroxy-2,3-diaryl(aralkyl)benzo[b]-thiophenes (2). The latter compounds yield 3,3-diaryl(aralkyl)-benzo[b]thiophene-2-ones (3) by pinacolone rearrangement. Treatment of 3 by hot ethanolic sodium hydroxide solution yields the corresponding carboxylic acids by hydrolytic heteroring opening.