F. Attaby, L. I. Ibrahim, S. M. Eldin
Dec 1, 1992
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0
Influential Citations
34
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Journal
Phosphorus Sulfur and Silicon and The Related Elements
Abstract
Abstract The ylidene derivatives of cyanothioacetamide 1a–d reacted with ethyl acetoacetate to give the pyridinethiol derivatives 2a–d. Compounds 2a–d were used as starting material for the synthesis of several heterocyclic compounds. Reactions with hydrazine hydrate, ethyl iodide, methyl chloroacetate and α-chloro ethyl acetoacetate gave the pyridine and annelated pyridine derivatives 5a–d, 6a–d, 7a, 8b–d, and 12a–d, respectively. Compounds 7a, 8b–d and 12a–d reacted with hydrazine hydrate to yield the annelated pyridines 10a–d and 15a–d, respectively.