S. Roberts
1985
Citations
0
Influential Citations
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Citations
Journal
Ciba Foundation symposium
Abstract
(+/-)-Bicyclo[3.2.0]hept-2-en-6-one was reduced using a variety of fungi including yeasts. Baker's yeast gave 6-exo-(1R,5S,6S)-bicyclo[3.2.0]hept-2-en-6-ol and 6-endo-(1S,5R,6S)-bicyclo[3.2.0]hept-2-en-6-ol while Curvularia lunata and Mortierella ramanniana gave only the 6-endo-alcohol and optically active bicycloheptenone. The optically active bicycloheptenols were used to prepare prostaglandin F2 alpha in the natural configuration.