V. Berseneva, V. Bakulev, W. Dehaen
May 21, 2007
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0
Influential Citations
13
Citations
Journal
Tetrahedron
Abstract
Abstract We report an efficient one-step approach to 4-thio and 4-aminopyrrolo[3,4- c ]pyridines based on the selective reaction of malonthioamides and malonamidines with methyl acetylpyruvate. Structural proof is given by HMBC and HMQC spectra. A cascade heterocyclization mechanism is proposed for the reactions studied.