K. Imafuku, Yumiko Miyashita, S. Kikuchi
2003
Citations
0
Influential Citations
5
Citations
Journal
Heterocycles
Abstract
Methyl 3-bromoacetylazulene-1-carboxylate (1) reacted with 2-aminopyridines (2a-f) to give methyl 3-(imidazo[1,2-a]pyrid-2-yl)azulene-1-carboxylates (3a-f). Similarly, the reactions with 2-aminopyrimidines (5a-c) and 2-amiono-1,2,4-triazines (8 a, b) gave the corresponding imidazo[1,2-a]pyrimidine-(6a-c) and imidazo[1,2-b][1,2,4]triazine-substitutrd azulenes (9a, b), respectively. Additionally, the substitution products (4 e, f and 7c) were isolated.