I. Gerus, Natalie V. Lyutenko, Alexey D. Kacharov
Dec 16, 2000
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The NH and α-CH insertion reactions of tosyl isocyanate with N -monosubstituted 4-amino-1,1,1-trifluorobut-3-en-2-ones have been studied. The regioselectivity of this reaction depends on the temperature, the nature of the solvent and the catalyst: high temperatures or basic catalysts direct in favour of NH insertion while low temperatures direct the process in favour of α-CH insertion.