T. Abdel-Rahman
May 1, 2006
Citations
0
Influential Citations
8
Citations
Quality indicators
Journal
Journal of Heterocyclic Chemistry
Abstract
The chemical reactivity of N-[1-(3-amino-6,8-dibromo-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-(2-chlorophenyl)-vinyl]benzamide (3) towards electrophilic and nucleophilic reagents have been reported. Structures of the products 3-24 have been confirmed by elemental analysis and spectral data (IR, 1H-NMR, 13C and MS). The bioassay indicates that some of the prepared compounds have a good selective anticancer activity.