G. Solladié, O. Lohse
Jul 1, 1993
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract (−) (1R, 2R, 5R)-5-methyl-2-(1-mercapto-1-methylethyl)-cyclohexanol was shown to be a very powerful agent for the optical resolution of ketones. It was used for the resolution of trans dimethyl cyclopentanone-3,4-dicarboxylate combined with the epimerization of the more soluble diastereomer, allowing an efficient second order asymmetric transformation to give the (SS) enantiomer in 80% yield.