D. Stetsenko, M. Gait
Oct 1, 2000
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0
Influential Citations
12
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract The preparation is described of four 2-cyanoethyl-N,N-diisopropyl phosphoramidites of N-α-Fmoc-S-protected cysteine hydroxyalkyl amides. The phosphoramidites were used in solid-phase synthesis of 5′-cysteinyl oligonucleotides, useful intermediates in the preparation of peptide-oligonucleotide conjugates through reaction with a maleimide peptide or with a peptide thioester via “native ligation”.