A. Mitra, T. Biswas, R. Ray
Nov 20, 1992
Citations
0
Influential Citations
1
Citations
Journal
Tetrahedron
Abstract
Abstract Catalytic dehydrogenation of 7′-methyl-1-hydroxyspiro [tetralin-2, 1′-tetralin] 5 and 7′-ethyl-7-methyl-1-hydroxyspiro [tetralin-2,1′-tetralin] 5a afforded 3-methylchrysene 7 and 3-ethyl-9-methylchrysene 7a respectively. Condensation of anhydride 1 of 1-carboxy-7-methyltetralin-1-acetic acid with benzene and that of anhydride 1a of 1-carboxy-7-ethyltetralin-1-acetic acid with toluene gave the corresponding keto-acids 2 and 2a which on catalytic reduction gave butyric acids 3 and 3a . Cyclisation of the acids ( 3 and 3a ) afforded the spiroketones 4 and 4a . Reduction with LAH of the spiroketones ( 4 and 4a ) gave the spiro-carbinols 5 and 5a .