T. Naito, R. Dohmori, T. Kotake
May 25, 1964
Citations
0
Influential Citations
12
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
Heating of N-phenylacetyl-2- and 4-pyridinesulfonamide 1-oxides in 10% sodium hydroxide at 90∼95°caused rearrangement reaction to form α-phenyl-2- and 4-pyridineacetic acid 1-oxides respectively. Their respective esterification and catalytic reduction with platinum-catalyst gave the hydrochloride of methyl 2- and 4-piperidineacetate and ethyl 2-piperidineacetate.