Young Kook Kim, Yun-Ho Lee, Hyang-Yeol Lee
Sep 20, 2003
Citations
0
Influential Citations
66
Citations
Journal
Organic letters
Abstract
[reaction: see text] A novel trifluoroacetophenone-based binding motif has been developed that recognizes anions such as carboxylates through reversible formation of anion-ionophore adducts that are stabilized by intramolecular H-bonding. The intramolecular H-bonding resulted in more than 10-fold enhancement in the binding affinity and an enthalpy gain (DeltaH degrees ) of 3.0 kcal/mol for the binding of an acetate ion when compared to the case without the intramolecular H-bonding.