Ramon Berenguer, Jordi García, J. Vilarrasa
1994
Citations
0
Influential Citations
30
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract ( R )- B -methyl-4,5,5-triphenyl-1,3,2-oxazaborolidine ( 1 ) and ( R )- B -allyl-4,5,5-triphenyl-1,3,2-oxazaborolidine ( 2 ), prepared from ( R )-phenylglycine, catalyse the reduction of prochiral ketones with borane, to afford the corresponding secondary alcohols in good chemical yields and with moderate to high (61%–96%) enantiomeric excesses. These compounds gave the best results reported so far regarding the reduction of linear alkyl methyl ketones catalysed by oxazaborolidines.