F. Fabiola, V. Pattabhi, E. Raju
Jan 12, 2009
Citations
0
Influential Citations
2
Citations
Journal
The journal of peptide research : official journal of the American Peptide Society
Abstract
The crystal structure of Boc-Val1-Pro2-(D)Asp3-Asp4-Val5-OMe is described as a type II beta-turn reengineered into a potential helix nucleator. (D)Asp3 in the peptide is responsible for the configurationally guided LD chiral type II beta-turn centered at Pro2-(D)Asp3, as well as the partially developed LL chiral type I beta-turn centered at Asp4-Val5 by acceptance of a conformation nucleating H-bond from Val5NH to its carboxylic oxygen.