Yann Brouillette, Guillaume Sujol, Jean Martínez
Jan 9, 2009
Citations
0
Influential Citations
3
Citations
Journal
Synthesis
Abstract
Convenient syntheses of optically pure 3-(2-thienyl)imidazolidine-2,4-dione (35-63% yields) and 3,4-dihydro-1H-thieno[2,3-e][1,4]diazepine-2,5-dione (35-81% yields) analogues are described. The regioselective ring opening of 1H-thieno[2,3-d][1,3]oxazine-2,4-dione (3-thiaisatoic anhydride), using inexpensive natural and synthetic α-amino acids under aqueous conditions, has been investigated to afford two libraries in a one-pot process.