Marcos A. P. Martins and
2003
Citations
1
Influential Citations
3
Citations
Journal
ChemInform
Abstract
Synthesis 2002, No. 16, Print: 14 11 2002. Art Id.1437-210X,E;2002,0,16,2353,2358,ftx,en;M02702SS.pdf. © Georg Thieme Verlag Stuttgart · New York ISSN 0039-7881 Abstract: A series of twelve 5-bromo[5,5-dibromo]-4-methoxy1,1,1-trihalo-3-alken-2-ones 5a–d, 6a–d, 7a, 9a, 10a and 6-bromo5-methoxy-1,1,1,2,2-pentafluoro-4-hexen-2-one (8a) were synthesized in high purity and good yields (70–95%) by the regiospecific allylic bromination of 4-methoxy-1,1,1-trihalo-3-alken-2-ones 1a– d, 2a–d, 3a or 5-methoxy-1,1,1,2,2-pentafluoro-4-hexen-2-one (4a), respectively, with bromine followed by addition of pyridine. The usefulness of compounds 5–10 in heterocyclic synthesis is also reported.