M. Katoh, S. Iwahara
1983
Citations
0
Influential Citations
3
Citations
Journal
The Japanese Journal of Genetics
Abstract
A high dose (200mg/kg) of isopropyl methanesulfonate (iPMS) induced a high frequency of postimplantation loss in postmeiotic male germ cell stages, but the frequency of eggs with chromosome aberrations observed at the first cleavage metaphases was very low. Therefore, we suggest that the postimplantation loss in dominant lethal mutations induced by iPMS is mainly attributable to the alteration of subchromosome material at the first cleavage metaphases.