P. Cohen, S. Frame
Oct 1, 2001
Citations
102
Influential Citations
1,511
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Journal
Nature Reviews Molecular Cell Biology
Abstract
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.