Stephanos Ioannidis, M. Lamb, L. Almeida
Mar 1, 2010
Citations
0
Influential Citations
23
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
Thiazol-2-yl amine was identified as an isosteric replacement for pyrazol-3-yl amine during our efforts to identify potent and selective JAK2 inhibitors. The rationale, synthesis and biological evaluation of several analogs is reported, along with the in vivo evaluation of the lead compounds.