Zhang Guan-chao
2011
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Journal
Fine and Specialty Chemicals
Abstract
Fexofenadine hydrochloride((±)-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-l-piperdidinyl]-butyl] -α,α-dimethyl benzeneacetic acid hydrochloride) is a new antiallergic drug,which can treat the allergic rhinitis. It can be synthesized based on the followings:α,α-dimethylphenylacetic acid's derivatives.benzyl cyanide,α,α-dimethylphenylacetic acid,α-methyl ethyl acrylate and other materials.