Xiao Sheng-xian
2007
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0
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Journal
Journal of Jiangxi Normal University
Abstract
Non-steroidal anti-fever drug indermediate 4-bromo-2-fluorobiphenyl was synthesiged from 2-fluoroaniline via NBS-bromination,diagonigation and ring-substitation.The reaction condition for every step were discussed,the accepting rate can be up to 80%,content≥97.5%.